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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 8th September 2025 Vol. No. 14 ; Issue No.700
Publications

1. Shetty MP, Tambe P, Rana K, Kulkarni SD, Chaudhari P, Bharati S (2025).Phosphorylation Enhanced the anti-cancer Therapeutic Activity of Larix sibirica-derived Arabinogalactan in Hepatocellular Carcinoma. Cell Biochemistry and Biophysics.

2. Puri S, Chaudhary I, Khatri A, Patel B, Kumawat A, Palkar S, Das G, Venkatraman P (2025). The Conformational Landscape of AlphaFold2-Predicted Amyloidogenic Light Chains and Their Correlation With VL Domain Mutations and Aggregation Propensity. Journal of Molecular Recognition. 38(5):e70011.

3. Nzufo F, Pieme C, Meher RK, Jouda J-B, Etsassala N, Pradhan T, Nirmal Kumar K., Sen S, Barkume M, Kumar S, Mir S, Kode J (2025). A traditional Cameroonian spice, Syzygium guineense curtails leukemia tumor growth through G2-M cell cycle arrest and predicted NLRP3 inflammasome pathway.Journal of Ayurveda and Integrative Medicine. 16(5):101202.

4. Kumari A, Mal A, Thorat R, Saha P, Patel P, Valvi S, CM Krishna, De A, Bandyopadhyaya R (2025). Sustained and localized delivery of gemcitabine using chitosan-PVA-TPP polymeric implant enhances antitumor efficacy and delays surgical relapse in pancreatic cancer. Biomaterials Advances.

5. Pai V, Wairkar T, Menon S, Chaudhari S, Deodhar K, Gupta A, Mittal P, Sawant P, Ghosh J, Rath S, Gupta S, Chopra S (2025). PD-L1 expression in locally advanced cervical cancer: A pilot cross clone comparison study. International Journal of Radiation Oncology Biology Physics.

Site of the Week

The Genotype-Tissue Expression (GTEx) Portal is a comprehensive public resource for researchers studying tissue and cell-specific gene expression and regulation across individuals, development, and species, with data from 3 NIH projects.

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Interesting Reads

DeMichele A, Clark AS, Shea E, Bayne LJ, Sterner CJ, Rohn K, Dwyer S, Pan TC, Nivar I, Chen Y, Wileyto P, Berry LR, Deluca S, Savage J, Makhlin I, Pant DK, Martin H, Egunsola A, Mears N, Goodspeed BL, Chislock EM, Graves J, Wang J, Shih N, Belka GK, Berry D, Nayak A, Feldman M, Chodosh LA (2025). Targeting dormant tumor cells to prevent recurrent breast cancer: a randomized phase 2 trial. Nature Medicine.

Video of the Week
DNA Methylation Profiling in CNS Tumor Diagnosis: applications and challenges
Upcoming Events
TMC Annual Radiotherapy Practicum 2025

September 12-13, 2025

At Proton Therapy Centre, ACTREC, Kharghar

Anaesthesia Review Course 2025

October 1-2, 2025,

At ACTREC, Tata Memorial Centre, Kharghar

21st Annual Live Surgical Oncology Workshop

November 20-222, 2025

At ACTREC, Tata Memorial Centre, Kharghar

Do You Know?

In 2012, Smart-seq, a method to generate high-coverage transcriptomes from single cells, is used to analyse the full-length messenger-RNA transcriptomes of circulating tumour cells from a patient with melanoma.

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Cancer News
Brain tumours in mice grow more slowly when starved of key amino acid.

Nature, 03/09/2025

The scientists fed mice with certain kinds of glioblastoma a diet that lacked serine and found that the rodents’ tumours, unable to get their fix the usual way, grew more slowly. The animals also lived longer...

Key gene linked to recurrent brain tumors provides a potential treatment target.

MedicalXpress, 03/09/2025

A research team has identified a novel therapeutic target for recurrent meningioma through precision genomic analysis. By performing single-cell RNA profiling of recurrent meningiomas, the team systematically mapped the tumor's evolutionary process and its...

Smoking fuels pancreatic cancer growth through immune suppression.

News-Medical, 04/09/2025

Researchers started by giving a chemical found in cigarettes and other environmental toxins to mice that had pancreatic tumors. They were looking to see how that would impact Interleukin-22, or IL22...

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